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Asia-Pacific Journal of Public Health
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The Prevalence of Antibody to Hepatitis A Virus in Singapore

K T Goh, MBBS, MSc

Quarantine and Epidemiology Department, Ministry of the Environment, 40 Scotts Road, Singapore 0922

L YM Wong, BSc, MSc

University Department of Medicine (I), Singapore General Hospital

C J Oon, MD, FRCP, DCH

University Department of Medicine (I), Singapore General Hospital

S Kumarapathy, MBBS, DPH

Drug Rehabilitation Centres, Ministry of Home Affairs

Sera collected from 1, 630 healthy children and adults aged between six months and 55 years during the period 1984 to 1985 were tested for hepatitis A virus (HAV) immunoglobulin G antibody by enzyme immunoassay. The over all antibody prevalence rate was 31.8%. It increased from 0% in children under five years old to 15.5% in adolescents and young adults (15 to 24 years) and reached the highest level of 88.2% in adults over 55 years of age. No statistically significant differences in the overall prevalence by sex and ethnic group were observed. None of the 938 samples tested for HAV immunoglobin M antibody was positive. Compared with the data in 1975, the survey showed that the level of exposure of Singapore children to HAV was declining as the result of vast socio-economic progress made during the past decade.

Key Words: Antibody to hepatitis A virus • Seroepidemiology • Singapore

Asia-Pacific Journal of Public Health, Vol. 1, No. 2, 9-11 (1987)
DOI: 10.1177/101053958700100203
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