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Hepatitis B Infection in Vanuatu: Age of Acquisition of Infection and Possible Routes of TransmissionFormerly Epidemiologist, South Pacific Commission, Noumea, New Caledonia Presently Senior Lecturer, Department of Public Health University of Sydney, NSW 2006, Australia
Formerly Epidemiologist, Department of Health, Port Vila, Vanuatu
Formerly Health Surveys Epidemiologist, South Pacific Commission Noumea, New Caledonia
Director, Macfarlane Burnet Centre for Medical Research
Director, Institut Pasteur, Noumea, New Caledonia
Macfarlane Burnet Centre for Medical Research, Fairfield Hospital for Infectious Diseases Melbourne, VIC, Australia
Epidemiologist, South Pacific Commission, Noumea, New Caledonia
Institut Pasteur, Noumea, New Caledonia
Institut Pasteur, Noumea, New Caledonia
South Pacific Commission, Noumea, New Caledonia Seroepidemiological studies of hepatitis B were carried out on diverse groups of children (477) and adults (629) from the Pacific Island country of Vanuatu. In children under 14 years, prevalences of HBsAg and of all markers were 6% and 53.3% respectively; in adults 20 years the prevalences were 15% and 70%. Age specific prevalence of hepatitis B infection (all markers) was low in infancy (< 1 year) but rose sharply afterwards, suggesting that the main mechanism of transmission was horizontal spread. This finding is consistent with other developing country studies from the Pacific Islands and elsewhere. In view of the main ages and mechanisms of transmission of hepatitis B in children in developing countries and the need for simple and inexpensive immunisation strategies in this context, it is recommended that mass vaccination of all infants with hepatitis B vaccine be undertaken in hyperendemic areas.
Key Words: hepatitis B hepatitis B antigen hepatitis B antibody Vanuatu Pacific Islands children age of acquisition of infection immunisation strategies
Asia-Pacific Journal of Public Health, Vol. 3, No. 3,
205-212 (1989) | ||