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Asia-Pacific Journal of Public Health
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The Seroepidemiology of Hepatitis A and B in a Japanese Town

S.M. Fazle Akbar, M.B.B.S.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Morikazu Onji, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Mitso Kanaoka, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Norio Horiike, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Kojiro Michitaka, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Toshikazu Masumoto, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Takashi Nonaka, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Kimitoshi Kanda, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Kazunori Kajino, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Izumi Kumamoto, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Seijin Nadano, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Yasuyuki Ohta, M.D.

Third Department of Internal Medicine, Ehime University School of Medicine, Shigenobu-Cho, Onsen-Gun, Ehime 791-02, Japan.

Sera collected from 1, 118 healthy children and adults aged between four years and 90 years during the period 1989 to 1990, were tested for serological markers of hepatitis A virus (HAV) [antibody to HAV(anti-HAV)] and hepatitis B virus (HBV) [hepatitis B surface antigen (HBsAg) and antibody to hepatitis B surface antigen (anti-HBsAb)]. The overall prevalence rates of anti-HAV, HBsAg, and anti-HBV were 20.2%, 0.36%, and 5.1%, respectively. No body was found to be positive for anti-HAV below 30 years of age but more than 70% of the adults aged 50 years or over were positive for anti-HAV. The level of exposure of HAV infection is declining in Japan and paradoxically at the same time a vast majority of people are becoming susceptible to more severe illness. The fall in prevalence of HBsAg possibly represents the positive impact of ongoing vaccination programs and other preventive measures against HBV.

Key Words: Anti-HAV • Anti-HBs • Hepatitis A vaccine • Hepatitis B surface antigen • HBV vaccine • Japan • Seroepidemiology

Asia-Pacific Journal of Public Health, Vol. 6, No. 2, 26-29 (1992)
DOI: 10.1177/101053959300600204
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